Skeletal Abnormalities in Mice Lacking Extracellular Matrix Proteins, Thrombospondin-1, Thrombospondin-3, Thrombospondin-5, and Type IX Collagen

Thrombospondin-5 (TSP5) is a large extracellular matrix glycoprotein found in musculoskeletal tissues. TSP5 mutations cause two skeletal dysplasias, pseudoachondroplasia and multiple epiphyseal dysplasia; both show a characteristic growth plate phenotype with retention of TSP5, type IX collagen (Col...

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Hauptverfasser: Posey, Karen L., Hankenson, Kurt, Veerisetty, Alka C., Bornstein, Paul, Lawler, Jack, Hecht, Jacqueline T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2008
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Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408425/
https://ncbi.nlm.nih.gov/pubmed/18467703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071094
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