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Chondrocyte-Specific Pathology During Skeletal Growth and Therapeutics in a Murine Model of Pseudoachondroplasia

Mutations in the gene encoding cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia (PSACH), a severe dwarfing condition. Pain, a significant complication, has generally been attributed to joint abnormalities and erosion and early onset osteoarthritis. Previously, we found that the...

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Detalhes bibliográficos
Main Authors: Posey, Karen L, Coustry, Francoise, Veerisetty, Alka C, Liu, Peiman, Alcorn, Joseph L, Hecht, Jacqueline T
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075045/
https://ncbi.nlm.nih.gov/pubmed/24194321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2139
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