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Genetic requirements for mycobacterial survival during infection

Despite the importance of tuberculosis as a public health problem, we know relatively little about the molecular mechanisms used by the causative organism, Mycobacterium tuberculosis, to persist in the host. To define these mechanisms, we have mutated virtually every nonessential gene of M. tubercul...

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Detalhes bibliográficos
Main Authors: Sassetti, Christopher M., Rubin, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC240732/
https://ncbi.nlm.nih.gov/pubmed/14569030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2134250100
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