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Characterization of mycobacterial virulence genes through genetic interaction mapping

We have previously shown that ≈5% of the genes encoded by the genome of Mycobacterium tuberculosis are specifically required for the growth or survival of this bacterium during infection. This corresponds to hundreds of genes, most of which have no identifiable function. As a unique approach to char...

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Detalhes bibliográficos
Main Authors: Joshi, Swati M., Pandey, Amit K., Capite, Nicole, Fortune, Sarah M., Rubin, Eric J., Sassetti, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544243/
https://ncbi.nlm.nih.gov/pubmed/16868085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603179103
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