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Characterization of mycobacterial virulence genes through genetic interaction mapping

We have previously shown that ≈5% of the genes encoded by the genome of Mycobacterium tuberculosis are specifically required for the growth or survival of this bacterium during infection. This corresponds to hundreds of genes, most of which have no identifiable function. As a unique approach to char...

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Bibliografiske detaljer
Main Authors: Joshi, Swati M., Pandey, Amit K., Capite, Nicole, Fortune, Sarah M., Rubin, Eric J., Sassetti, Christopher M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544243/
https://ncbi.nlm.nih.gov/pubmed/16868085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603179103
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