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Mutually dependent secretion of proteins required for mycobacterial virulence

The ESX-1 locus is a region critical for full virulence in Mycobacterium tuberculosis, which encodes two secreted proteins as well as other genes involved in their secretion. The mechanism of secretion of the two proteins, ESAT-6 and CFP-10, and their function remain unknown. Using proteomic methods...

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Bibliografiset tiedot
Päätekijät: Fortune, S. M., Jaeger, A., Sarracino, D. A., Chase, M. R., Sassetti, C. M., Sherman, D. R., Bloom, B. R., Rubin, E. J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1176248/
https://ncbi.nlm.nih.gov/pubmed/16030141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504922102
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