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Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens

Conventionally, MHC class I-restricted antigen (Ag) processing requires the action of the multimolecular peptide-loading complex within the endoplasmic reticulum (ER). Here we show that early phagosomes from human dendritic cells (DCs) contain the peptide-loading complex, incorporating MHC class I,...

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Autores principales: Ackerman, Anne L., Kyritsis, Christoph, Tampé, Robert, Cresswell, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC240714/
https://ncbi.nlm.nih.gov/pubmed/14561893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1735556100
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