Methylated DNA-binding domain 1 and methylpurine–DNA glycosylase link transcriptional repression and DNA repair in chromatin

The methyl–CpG dinucleotide containing a symmetrical 5-methylcytosine (mC) is involved in gene regulation and genome stability. We report here that methylation-mediated transcriptional repressor methylated DNA-binding domain 1 (MBD1) interacts with methylpurine–DNA glycosylase (MPG), which excises d...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Watanabe, Sugiko, Ichimura, Takaya, Fujita, Naoyuki, Tsuruzoe, Shu, Ohki, Izuru, Shirakawa, Masahiro, Kawasuji, Michio, Nakao, Mitsuyoshi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2003
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240709/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14555760/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2131819100
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