Methylated DNA-binding domain 1 and methylpurine–DNA glycosylase link transcriptional repression and DNA repair in chromatin

The methyl–CpG dinucleotide containing a symmetrical 5-methylcytosine (mC) is involved in gene regulation and genome stability. We report here that methylation-mediated transcriptional repressor methylated DNA-binding domain 1 (MBD1) interacts with methylpurine–DNA glycosylase (MPG), which excises d...

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Autors principals: Watanabe, Sugiko, Ichimura, Takaya, Fujita, Naoyuki, Tsuruzoe, Shu, Ohki, Izuru, Shirakawa, Masahiro, Kawasuji, Michio, Nakao, Mitsuyoshi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC240709/
https://ncbi.nlm.nih.gov/pubmed/14555760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2131819100
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