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Structure of tRNA pseudouridine synthase TruB and its RNA complex: RNA recognition through a combination of rigid docking and induced fit

RNA pseudouridine synthase, TruB, catalyzes pseudouridine formation at U55 in tRNA. This posttranscriptional modification is almost universally conserved and occurs in the T arm of most tRNAs. We determined the crystal structure of Escherichia coli TruB apo enzyme, as well as the structure of Thermo...

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Hlavní autoři: Pan, Hu, Agarwalla, Sanjay, Moustakas, Demetri T., Finer-Moore, Janet, Stroud, Robert M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC240672/
https://ncbi.nlm.nih.gov/pubmed/14566049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2135585100
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