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Intracellular Actions of Group IIA Secreted Phospholipase A(2) and Group IVA Cytosolic Phospholipase A(2) Contribute to Arachidonic Acid Release and Prostaglandin Production in Rat Gastric Mucosal Cells and Transfected Human Embryonic Kidney Cells

Gastric epithelial cells liberate prostaglandin E(2) in response to cytokines as part of the process of healing of gastric lesions. Treatment of the rat gastric epithelial cell line RGM1 with transforming growth factor-α and interleukin-1β leads to synergistic release of arachidonate and production...

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Detalhes bibliográficos
Main Authors: Ni, Zhanglin, Okeley, Nicole M., Smart, Brian P., Gelb, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2405944/
https://ncbi.nlm.nih.gov/pubmed/16603549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M513874200
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