Blastic transformation of p53-deficient bone marrow cells by p210(bcr/abl) tyrosine kinase

Blastic transformation of chronic myelogenous leukemia (CML) is characterized by the presence of nonrandom, secondary genetic abnormalities in the majority of Philadelphia(1) clones, and loss of p53 tumor suppressor gene function is a consistent finding in 25–30% of CML blast crisis patients. To tes...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Skorski, Tomasz, Nieborowska-Skorska, Malgorzata, Wlodarski, Pawel, Perrotti, Danilo, Martinez, Robert, Wasik, Mariusz A., Calabretta, Bruno
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences of the USA 1996
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC24059/
https://ncbi.nlm.nih.gov/pubmed/8917557
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