Deoxyadenosine reverses hydroxyurea inhibition of vaccinia virus growth.

Hydroxyurea, an inhibitor of ribonucleotide reductase, blocks replication of vaccinia virus. However, when medium containing hydroxyurea and dialyzed serum was supplemented with deoxyadenosine, the block to viral reproduction was circumvented, provided that an inhibitor of adenosine deaminase was al...

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Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Slabaugh, M B, Howell, M L, Wang, Y, Mathews, C K
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1991
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240578/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2016760/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.5.2290-2298.1991
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