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Deoxyadenosine reverses hydroxyurea inhibition of vaccinia virus growth.

Hydroxyurea, an inhibitor of ribonucleotide reductase, blocks replication of vaccinia virus. However, when medium containing hydroxyurea and dialyzed serum was supplemented with deoxyadenosine, the block to viral reproduction was circumvented, provided that an inhibitor of adenosine deaminase was al...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Slabaugh, M B, Howell, M L, Wang, Y, Mathews, C K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240578/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2016760/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.5.2290-2298.1991
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