Conformational epitope on gp120 important in CD4 binding and human immunodeficiency virus type 1 neutralization identified by a human monoclonal antibody.

A human monoclonal antibody designated 15e is reactive with the envelope glycoprotein (gp120) of multiple isolates of human immunodeficiency virus type 1 (HIV-1). Antibody 15e also neutralizes HIV-1 with broad specificity and blocks gp120 binding to CD4. Characterization of the 15e epitope shows tha...

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Publicado en:	J Virol
Autores principales:	Ho, D D, McKeating, J A, Li, X L, Moudgil, T, Daar, E S, Sun, N C, Robinson, J E
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1991
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1702163/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.1.489-493.1991
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