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Conformational epitope on gp120 important in CD4 binding and human immunodeficiency virus type 1 neutralization identified by a human monoclonal antibody.

A human monoclonal antibody designated 15e is reactive with the envelope glycoprotein (gp120) of multiple isolates of human immunodeficiency virus type 1 (HIV-1). Antibody 15e also neutralizes HIV-1 with broad specificity and blocks gp120 binding to CD4. Characterization of the 15e epitope shows tha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ho, D D, McKeating, J A, Li, X L, Moudgil, T, Daar, E S, Sun, N C, Robinson, J E
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1991
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC240544/
https://ncbi.nlm.nih.gov/pubmed/1702163
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