Mutagenesis of the Glu-89 residue in human immunodeficiency virus type 1 (HIV-1) and HIV-2 reverse transcriptases: effects on nucleoside analog resistance.

A Glu-89-->Gly alteration in the human immunodeficiency virus type 1 reverse transcriptase (RT) was previously shown to result in resistance to several dideoxynucleoside analogs and to phosphonoformic acid (PFA; foscarnet). This residue was altered to Ala, Val, Ser, Thr, Gln, Asp, Asn, or Lys, an...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Song, Q, Yang, G, Goff, S P, Prasad, V R
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1992
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC240471/
https://ncbi.nlm.nih.gov/pubmed/1279207
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk