Purification and characterization of poliovirus polypeptide 3CD, a proteinase and a precursor for RNA polymerase.

A cDNA clone encoding the 3CD proteinase (3CDpro) of poliovirus type 2 (Sabin), the precursor to proteinase 3Cpro and RNA polymerase 3Dpol, was expressed in bacteria by using a T7 expression system. Site-specific mutagenesis of the 3C/3D cleavage site was performed to generate active proteolytic pre...

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Argitaratua izan da:	J Virol
Egile Nagusiak:	Harris, K S, Reddigari, S R, Nicklin, M J, Hämmerle, T, Wimmer, E
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 1992
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240456/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1331532/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.12.7481-7489.1992
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