Antiviral effects of a thiol protease inhibitor on foot-and-mouth disease virus.

The thiol protease inhibitor E-64 specifically blocks autocatalytic activity of the leader protease of foot-and-mouth disease virus (FMDV) and interferes with cleavage of the structural protein precursor in an in vitro translation assay programmed with virion RNA. Experiments with FMDV-infected cell...

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Bibliographic Details
Published in:J Virol
Main Authors: Kleina, L G, Grubman, M J
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240409/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1331517/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.12.7168-7175.1992
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