Mutation of a cysteine residue in polyomavirus middle T antigen abolishes interactions with protein phosphatase 2A, pp60c-src, and phosphatidylinositol-3 kinase, activation of c-fos expression, and cellular transformation.

Ítems similars

• Altered sites of tyrosine phosphorylation in pp60c-src associated with polyomavirus middle tumor antigen.
  per: Cartwright, C A, et al.
  Publicat: (1986)
• pp60c-src binding to polyomavirus middle T-antigen (MT) requires residues 185 to 210 of the MT sequence.
  per: Brewster, C E, et al.
  Publicat: (1997)
• Myristylation of pp60c-src is not required for complex formation with polyomavirus middle-T antigen.
  per: Wyss, A, et al.
  Publicat: (1990)
• Novel monoclonal antibodies that differentiate between the binding of pp60c-src or protein phosphatase 2A by polyomavirus middle T antigen.
  per: Dilworth, S M, et al.
  Publicat: (1993)
• Simultaneous overexpression of avian pp60c-src and polyomavirus middle T antigen in mammalian cells.
  per: Cook, D N, et al.
  Publicat: (1990)