A recombinant human Fab expressed in Escherichia coli neutralizes rabies virus.

A recombinant human anti-rabies monoclonal antibody (MAb-57) Fab was prepared by cloning the heavy (Fd)- and light-chain domains into the same bacterial expression vector. To construct the recombinant Fab, mRNA was extracted from MAb-57-producing hybridoma cells, reverse transcribed, and then amplif...

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Pubblicato in:	J Virol
Autori principali:	Cheung, S C, Dietzschold, B, Koprowski, H, Notkins, A L, Rando, R F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240167/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1404611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.11.6714-6720.1992
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