Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity.

Respiratory syncytial virus (RSV) is the most important cause, throughout the world, of severe viral lower respiratory tract illness in young children. Antibodies are known to mediate resistance to RSV infection and illness. We have isolated a number of human monoclonal Fab fragments to RSV F glycop...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Barbas, C F, Crowe, J E, Cababa, D, Jones, T M, Zebedee, S L, Murphy, B R, Chanock, R M, Burton, D R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50298/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1279672/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.21.10164
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