Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity.

Respiratory syncytial virus (RSV) is the most important cause, throughout the world, of severe viral lower respiratory tract illness in young children. Antibodies are known to mediate resistance to RSV infection and illness. We have isolated a number of human monoclonal Fab fragments to RSV F glycop...

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Autors principals: Barbas, C F, Crowe, J E, Cababa, D, Jones, T M, Zebedee, S L, Murphy, B R, Chanock, R M, Burton, D R
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC50298/
https://ncbi.nlm.nih.gov/pubmed/1279672
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