Functional characterization of temperature-sensitive mutants of simian virus 40 large T antigen.
We investigated the molecular properties of eight temperature-sensitive mutants of simian virus 40 large T antigen (tsA mutants). The mutants have single amino acid substitutions that block DNA replication at 39 to 41 degrees C in vivo. In vitro, five of the mutant proteins were highly sensitive to...
में बचाया:
| में प्रकाशित: | J Virol |
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| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Microbiology (ASM)
1992
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240144/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1328677/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.11.6509-6516.1992 |
| टैग: |
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