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A zinc finger directory for high-affinity DNA recognition

We have used two monovalent phage display libraries containing variants of the Zif268 DNA-binding domain to obtain families of zinc fingers that bind to alterations in the last 4 bp of the DNA sequence of the Zif268 consensus operator, GCG TGGGCG. Affinity selection was performed by altering the Zif...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jamieson, Andrew C., Wang, Hongming, Kim, Sung-Hou
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1996
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24006/
https://ncbi.nlm.nih.gov/pubmed/8917505
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