A zinc finger directory for high-affinity DNA recognition
We have used two monovalent phage display libraries containing variants of the Zif268 DNA-binding domain to obtain families of zinc fingers that bind to alterations in the last 4 bp of the DNA sequence of the Zif268 consensus operator, GCG TGGGCG. Affinity selection was performed by altering the Zif...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1996
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24006/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8917505/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.23.12834 |
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