A zinc finger directory for high-affinity DNA recognition

We have used two monovalent phage display libraries containing variants of the Zif268 DNA-binding domain to obtain families of zinc fingers that bind to alterations in the last 4 bp of the DNA sequence of the Zif268 consensus operator, GCG TGGGCG. Affinity selection was performed by altering the Zif...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Jamieson, Andrew C., Wang, Hongming, Kim, Sung-Hou
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1996
主題:	Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24006/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8917505/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.23.12834
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