Dextran sulfate blocks antibody binding to the principal neutralizing domain of human immunodeficiency virus type 1 without interfering with gp120-CD4 interactions.

The mechanism of the antiviral activity of sulfated polysaccharides on human immunodeficiency virus type 1 (HIV-1) was investigated by determining the effect of dextran sulfate on the binding of CD4 and several anti-gp120 monoclonal antibodies to both recombinant and cell surface gp120. Dextran sulf...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Callahan, L N, Phelan, M, Mallinson, M, Norcross, M A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1991
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC239935/
https://ncbi.nlm.nih.gov/pubmed/1995952
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