Identification of two determinants that attenuate vaccine-related type 2 poliovirus.

The poliovirus P2/P712 strain is an attenuated virus that is closely related to the type 2 Sabin vaccine strain. By using a mouse model for poliomyelitis, sequences responsible for attenuation of the P2/P712 strain were previously mapped to the 5' noncoding region of the genome and a central region...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Ren, R B, Moss, E G, Racaniello, V R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239915/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1847458/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.3.1377-1382.1991
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