Determinants in the 5' noncoding region of poliovirus Sabin 1 RNA that influence the attenuation phenotype.

A number of recombinants between the virulent Mahoney and attenuated Sabin strains of type 1 poliovirus were constructed by using infectious cDNA clones of the two strains. To identify a strong neurovirulence determinant(s) residing in the genome region upstream of nucleotide position 1122, these re...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kawamura, N, Kohara, M, Abe, S, Komatsu, T, Tago, K, Arita, M, Nomoto, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247827/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536835/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.3.1302-1309.1989
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