Direct measurement of soluble CD4 binding to human immunodeficiency virus type 1 virions: gp120 dissociation and its implications for virus-cell binding and fusion reactions and their neutralization by soluble CD4.

We have analyzed the binding of soluble CD4 (sCD4) to human immunodeficiency virus type 1 (HIV-1) virions (isolates IIIB and RF) at 4 and 37 degrees C by using a combination of gel exclusion chromatography and enzyme-linked immunosorbent assay detection systems. The sCD4 binding curve at 37 degrees...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Moore, J P, McKeating, J A, Norton, W A, Sattentau, Q J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1995942/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.3.1133-1140.1991
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