Direct measurement of soluble CD4 binding to human immunodeficiency virus type 1 virions: gp120 dissociation and its implications for virus-cell binding and fusion reactions and their neutralization by soluble CD4.

We have analyzed the binding of soluble CD4 (sCD4) to human immunodeficiency virus type 1 (HIV-1) virions (isolates IIIB and RF) at 4 and 37 degrees C by using a combination of gel exclusion chromatography and enzyme-linked immunosorbent assay detection systems. The sCD4 binding curve at 37 degrees...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Moore, J P, McKeating, J A, Norton, W A, Sattentau, Q J
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1991
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239879/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1995942/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.3.1133-1140.1991
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