Tip60 Is Required for DNA Interstrand Cross-link Repair in the Fanconi Anemia Pathway

The disease Fanconi anemia is a genome instability syndrome characterized by cellular sensitivity to DNA interstrand cross-linking agents, manifest by decreased cellular survival and chromosomal aberrations after such treatment. There are at least 13 proteins acting in the pathway, with the FANCD2 p...

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Bibliografiske detaljer
Main Authors: Hejna, James, Holtorf, Megan, Hines, Jennie, Mathewson, Lauren, Hemphill, Aaron, Al-Dhalimy, Muhsen, Olson, Susan B., Moses, Robb E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2398728/
https://ncbi.nlm.nih.gov/pubmed/18263878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709076200
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