Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1.
The human immunodeficiency virus (HIV) genome codes for a trans-activating regulatory protein, tat. Using chemically synthesized tat, it was found that 125I-tat and 125I-tat38-86 specifically bound to rat brain synaptosomal membranes with moderate affinity (K0.5 = 3 microM). Interaction of tat with...
Uloženo v:
| Vydáno v: | J Virol |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1991
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239839/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1898974/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.2.961-967.1991 |
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