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The DNA-binding properties of polyomavirus large T antigen are altered by ATP and other nucleotides.
We have examined the influence of ATP on the DNA-binding properties of polyomavirus large T antigen (Py TAg). Utilizing nitrocellulose filter binding, DNase I footprinting, and gel mobility shift assays, we observed that ATP increased Py TAg binding to DNA fragments containing either all Py TAg-bind...
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| Udgivet i: | J Virol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1991
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239808/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846192/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.2.687-699.1991 |
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