Primary rat cells expressing a hybrid polyomavirus-simian virus 40 large T antigen have altered growth properties.
Expression of simian virus 40 (SV40) large T antigen efficiently immortalizes and transforms primary cells. We previously reported that a hybrid polyomavirus-SV40 large T antigen, PyT1-521-SVT336-708, binds to both p53 and pRb but does not transform an established rat cell line (J. J. Manfredi and C...
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| Udgivet i: | J Virol |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1993
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237861/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8392612/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.8.4750-4759.1993 |
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