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Primary rat cells expressing a hybrid polyomavirus-simian virus 40 large T antigen have altered growth properties.

Expression of simian virus 40 (SV40) large T antigen efficiently immortalizes and transforms primary cells. We previously reported that a hybrid polyomavirus-SV40 large T antigen, PyT1-521-SVT336-708, binds to both p53 and pRb but does not transform an established rat cell line (J. J. Manfredi and C...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Manfredi, J J, Prives, C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1993
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237861/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8392612/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.8.4750-4759.1993
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