The DNA-binding properties of polyomavirus large T antigen are altered by ATP and other nucleotides.

We have examined the influence of ATP on the DNA-binding properties of polyomavirus large T antigen (Py TAg). Utilizing nitrocellulose filter binding, DNase I footprinting, and gel mobility shift assays, we observed that ATP increased Py TAg binding to DNA fragments containing either all Py TAg-bind...

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Publicado en:J Virol
Autores principales: Lorimer, H E, Wang, E H, Prives, C
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1991
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239808/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846192/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.2.687-699.1991
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