Herpes simplex virus transactivator ICP4 operationally substitutes for the cellular transcription factor Sp1 for efficient expression of the viral thymidine kinase gene.

Ítems similars

• Substitution of a TATA box from a herpes simplex virus late gene in the viral thymidine kinase promoter alters ICP4 inducibility but not temporal expression.
  per: Imbalzano, A N, et al.
  Publicat: (1992)
• Functional relevance of specific interactions between herpes simplex virus type 1 ICP4 and sequences from the promoter-regulatory domain of the viral thymidine kinase gene.
  per: Imbalzano, A N, et al.
  Publicat: (1990)
• Activities of heterodimers composed of DNA-binding- and transactivation-deficient subunits of the herpes simplex virus regulatory protein ICP4.
  per: Shepard, A A, et al.
  Publicat: (1991)
• Separation of primary structural components conferring autoregulation, transactivation, and DNA-binding properties to the herpes simplex virus transcriptional regulatory protein ICP4.
  per: Shepard, A A, et al.
  Publicat: (1989)
• Requirements for activation of the herpes simplex virus glycoprotein C promoter in vitro by the viral regulatory protein ICP4.
  per: Gu, B, et al.
  Publicat: (1994)