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Hydrolysis of Phosphatidylinositol 4,5-Bisphosphate Mediates Calcium-induced Inactivation of TRPV6 Channels

TRPV6 is a member of the transient receptor potential superfamily of ion channels that facilitates Ca(2+) absorption in the intestines. These channels display high selectivity for Ca(2+), but in the absence of divalent cations they also conduct monovalent ions. TRPV6 channels have been shown to be i...

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Main Authors: Thyagarajan, Baskaran, Lukacs, Viktor, Rohacs, Tibor
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397461/
https://ncbi.nlm.nih.gov/pubmed/18390907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M704224200
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