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Molecular Force Balance Measurements Reveal that Double-Stranded DNA Unbinds Under Force in Rate-Dependent Pathways

Strand separation of double-stranded DNA is a crucial step for essential cellular processes such as recombination and transcription. By means of a molecular force balance, we have analyzed the impact of different pulling directions and different force-loading rates on the unbinding process of short...

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Detalhes bibliográficos
Main Authors: Albrecht, Christian H., Neuert, Gregor, Lugmaier, Robert A., Gaub, Hermann E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397355/
https://ncbi.nlm.nih.gov/pubmed/18339733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.125427
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