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Predicting the Rupture Probabilities of Molecular Bonds in Series

An assembly of two receptor ligand bonds in series will typically break at the weaker complex upon application of an external force. The rupture site depends highly on the binding potentials of both bonds and on the loading rate of the applied force. A model is presented that allows simulations of f...

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Autors principals: Neuert, Gregor, Albrecht, Christian H., Gaub, Hermann E.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929050/
https://ncbi.nlm.nih.gov/pubmed/17468164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.100511
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