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Salt-Mediated Electrostatics in the Association of TATA Binding Proteins to DNA: A Combined Molecular Mechanics/Poisson-Boltzmann Study

The TATA-binding protein (TBP) is a key component of the archaea ternary preinitiation transcription assembly. The archaeon TBP, from the halophile/hyperthermophile organism Pyrococcus woesei, is adapted to high concentrations of salt and high-temperature environments. Although most eukaryotic TBPs...

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Bibliografske podrobnosti
Main Authors: Bredenberg, Johan H., Russo, Cristina, Fenley, Marcia O.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397334/
https://ncbi.nlm.nih.gov/pubmed/18326635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.125609
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