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Problems of Robustness in Poisson–Boltzmann Binding Free Energies

[Image: see text] Although models based on the Poisson–Boltzmann (PB) equation have been fairly successful at predicting some experimental quantities, such as solvation free energies (ΔG), these models have not been consistently successful at predicting binding free energies (ΔΔG). Here we found tha...

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Detalhes bibliográficos
Publicado no:J Chem Theory Comput
Main Authors: Harris, Robert C., Mackoy, Travis, Fenley, Marcia O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610304/
https://ncbi.nlm.nih.gov/pubmed/26528091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct5005017
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