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Poisson-Boltzmann Calculations of Nonspecific Salt Effects on Protein-Protein Binding Free Energies

The salt dependence of the binding free energy of five protein-protein hetero-dimers and two homo-dimers/tetramers was calculated from numerical solutions to the Poisson-Boltzmann equation. Overall, the agreement with experimental values is very good. In all cases except one involving the highly cha...

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Bibliografske podrobnosti
Main Authors: Bertonati, Claudia, Honig, Barry, Alexov, Emil
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861767/
https://ncbi.nlm.nih.gov/pubmed/17208980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.092122
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