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Variant-specific [PSI(+)] Infection Is Transmitted by Sup35 Polymers within [PSI(+)] Aggregates with Heterogeneous Protein Composition

The [PSI(+)] prion is the aggregated self-propagating form of the Sup35 protein from the yeast Saccharomyces cerevisiae. Aggregates of Sup35 in [PSI(+)] cells exist in different heritable conformations, called “variants,” and they are composed of detergent-resistant Sup35 polymers, which may be clos...

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Bibliografiske detaljer
Main Authors: Bagriantsev, Sviatoslav N., Gracheva, Elena O., Richmond, Janet E., Liebman, Susan W.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397312/
https://ncbi.nlm.nih.gov/pubmed/18353968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-01-0078
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