R-Spondin Family Members Regulate the Wnt Pathway by a Common Mechanism

The R-Spondin (RSpo) family of secreted proteins is implicated in the activation of the Wnt signaling pathway. Despite the high structural homology between the four members, expression patterns and phenotypes in knockout mice have demonstrated striking differences. Here we dissected and compared the...

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Autori principali: Kim, Kyung-Ah, Wagle, Marie, Tran, Karolyn, Zhan, Xiaoming, Dixon, Melissa A., Liu, Shouchun, Gros, Delphine, Korver, Wouter, Yonkovich, Shirlee, Tomasevic, Nenad, Binnerts, Minke, Abo, Arie
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397303/
https://ncbi.nlm.nih.gov/pubmed/18400942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-02-0187
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