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The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching

Blood vessel formation requires the integrated regulation of endothelial cell proliferation and branching morphogenesis, but how this coordinated regulation is achieved is not well understood. Flt-1 (vascular endothelial growth factor [VEGF] receptor 1) is a high affinity VEGF-A receptor whose loss...

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Detalhes bibliográficos
Main Authors: Kappas, Nicholas C., Zeng, Gefei, Chappell, John C., Kearney, Joseph B., Hazarika, Surovi, Kallianos, Kimberly G., Patterson, Cam, Annex, Brian H., Bautch, Victoria L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396811/
https://ncbi.nlm.nih.gov/pubmed/18504303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200709114
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