STAT3-Mediated Up-Regulation of BLIMP1 Is Coordinated with BCL6 Down-Regulation to Control Human Plasma Cell Differentiation

STAT family members have been implicated in regulating the balance between B cell lymphoma (BCL)6 and B lymphocyte induced maturation protein (BLIMP)1 to control plasma cell differentiation. We previously showed that STAT5 induces BCL6 to block plasma cell differentiation and extend the life span of...

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Hlavní autoři: Diehl, Sean A., Schmidlin, Heike, Nagasawa, Maho, van Haren, Simon D., Kwakkenbos, Mark J., Yasuda, Etsuko, Beaumont, Tim, Scheeren, Ferenc A., Spits, Hergen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396731/
https://ncbi.nlm.nih.gov/pubmed/18354204
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