Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression

The terminal differentiation of B cells into antibody-secreting plasma cells is tightly regulated by a complex network of transcription factors. Here we evaluated the role of the Ets factor Spi-B during terminal differentiation of human B cells. All mature tonsil and peripheral blood B-cell subsets...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schmidlin, Heike, Diehl, Sean A., Nagasawa, Maho, Scheeren, Ferenc A., Schotte, Remko, Uittenbogaart, Christel H., Spits, Hergen, Blom, Bianca
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518887/
https://ncbi.nlm.nih.gov/pubmed/18552212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-136440
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados