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High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

Site-directed spin labeling has qualitatively shown that a key event during activation of rhodopsin is a rigid-body movement of transmembrane helix 6 (TM6) at the cytoplasmic surface of the molecule. To place this result on a quantitative footing, and to identify movements of other helices upon phot...

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Autori principali: Altenbach, Christian, Kusnetzow, Ana Karin, Ernst, Oliver P., Hofmann, Klaus Peter, Hubbell, Wayne L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396682/
https://ncbi.nlm.nih.gov/pubmed/18490656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802515105
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